高伟

点击数:   更新日期: 2021-04-26


高伟   教授、硕士生导师


电子邮箱: gaowei_box@163.com

办公电话: 010-62338136


研究方向


生物大分子结构与功能


教育工作经历


2001.9?2005.1 中国科学院生物物理所, 博士

1998.9?2001.7 中国农科院生物技术所, 硕士

1987.9?1991.7 郑州大学, 学士

2005-至今 LD乐动体育官方欢迎您的加入 副教授、教授


主讲课程


《生物物理学》、《大学物理学》、《物理与人类文明》


奖励及荣誉称号


教育部新世纪优秀人才

北京市第五届青年教师基本功比赛三等奖

校优秀硕士、本科生导师


学术/社会兼职


protein and peptide letters 审稿人


工作及成果展示


科研项目

1.北京林业大学重大科研成果, 中国传统菊花品种起源和进化的遗传研究, 16,在研, 参加.

2.北京林业大学青年教师科学研究中长期项目, 林业测量仪器平台建设与应用, 50万元, 在研, 参加.

3.国家自然科学基金面上项目, 31070651、植物特有的类神经钙素B与激酶复合物(CBL1-CIPK23)的晶体结构测定及功能研究, 35万元, 主持.

4.国家自然科学基金面上项目, 30970578、植物特有的类神经钙素B蛋白及相互作用激酶复合物的晶体结构测定与抗性功能关系的研究, 8万元, 主持.

5.国家自然科学基金重点项目, 30730077 调控杨树耐旱节水性状的功能基因组学研究、150万元、参加.

6.教育部新世纪优秀人才, 2008, 林业科学.

7.国家林业局重点项目, 2006-59、抗杨树虫害的蛋白酶抑制剂类制剂的开发研究, 20万元、主持.


发表论文

(1) Salinas, Gustavo(*); Gao, Wei(#); Wang, Yang; Bonilla, Mariana; Yu, Long; Dai,Shaodong(*) The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I) , ANTIOXIDANTS & REDOX SIGNALING, 2017.12.20, 27(18): 1491~1504

(2) Lu, Fang; Zhang, Bei; Liu, Yong; Song, Ying; Guo, Gangxing; Feng, Duo;Huang, Huoqing; Yang, Peilong; Gao, Wei(*) ; Guo, Sujuan(*) ; Yao, Bin(*) Crystallization and X-ray diffraction analysis of native and selenomethionine-substituted PhyH-DI from Bacillus sp HJB17 , ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2017.11, 73:607~611

(3) Zhao Qihong; Liu Jie; Xu Xiao; Xu Qian; Gao Wei(*); Xu JichenPicW orthologs from spruce with differential freezing tolerance expressed in Escherichia coli , INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017.8,101: 595~602

(4)Liu Yong; Lu Fang; Guo Gang-Xing; Feng Duo; Zhang Bei; Gao Wei ; BiRu-Chang(*), Crystallization and Preliminary Crystallographic Analysis of Thioredoxin-dependent Thiol Peroxidase (SF2523) From Shigella flexneri 2a str.301 , 生物化学与生物物理进展, 2017.3, 44(3): 253~258

(5)Lu, Fang ; Guo, Gangxin; Li, Qianqian; Feng, Duo; Liu, Yong; Huang,Huoqing; Yang, Peilong; Gao, Wei(*); Yao, Bin(*),Preparation, purification, crystallization and preliminary crystallographic analysis of dual-domain beta-propeller phytase from Bacillus sp HJB17 , Acta Crystallographica Section F-Structural Biology Communications, 2014.12, 70: 1671~1674

(6) Shang, Guijun; Feng, Duo; Lu, Fang; Zhang, Hongjie; Cang, Huaixing; Gao, Wei(*); Bi, Ruchang,Purification, crystallization and preliminary crystallographic analysis of a ribosome-recycling factor from Thermoanaerobacter tengcongensis (TteRRF) , ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2014.5, 70: 588~591

(7)Shang, Guijun; Cang, Huaixing; Liu, Zhijie; Gao, Wei ; Bi, Ruchang,(*)Crystallization and preliminary crystallographic analysis of a calcineurin B-likeprotein 1 (CBL1) mutant from Ammopiptanthus mongolicus , Acta Crystallographica Section F-Structural Biology and Crystallization Communications,2010.12, 66: 1602~1605

(8)Yuan, Daopeng; Wang, Qihai; Gao, Wei ; Sheng, Fanyi; Zhang, Zhanyu;(*)Lu, Qingyu; Cang, Huaixing; Bi, Ruchang, Cloning, expression, purification, characterization, crystallization and X-ray diffraction of bifunctionalpyrimidine deaminase/reductase from Shigella flexneri 2a , Protein and Peptide Letters, 2007,14(9)925-927

(9)Gao, Wei; Starkov, Vladislav G.; He, Zi-xuan; Wang, Qi-hai; Tsetlin,Victor I.; Utkin, Yuri N.; Lin, Zheng-jiong; Bi, Ru-chang,(*) Functions,structures and Triton X-100 effect for the catalytic subunits of heterodimeric phospholipases A(2) from Vipera nikolskii venom , Toxicon, 2009.11, 54(6):709~716

(10) Li, Shu-Xing ; Tong, Yong-Ping; Xie, Xiao-Cong; Wang, Qi-Hai; Zhou,(#)Hui-Na; Han, Yi; Zhang, Zhan-Yu; Gao, We; Li, Sheng-Guang; Zhang, Xuejun C.;Bi, Ru-Chang(*) Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis , Journal of Molecular Biology, 2007.3.9, 366(5):1603~1614


专利

(1) 高伟; 鲁芳; 李倩倩; 郭刚兴, 一种大量制备双功能域β-折叠桶植酸酶二体的方法, 2014.4.23, 中国, CN201410006180.4 (专利)

(2) 高伟, 一种豇豆胰蛋白酶抑制剂基因、及其应用、大量制备豇豆胰蛋白酶抑制剂的方法, 2010.12.8, 中国, CN201010590327.0 (专利)